I-17α-Hydroxyprogesterone CAS 68-96-2

Isingeniso 17 α- Hydroxyprogesterone, ngezinye izikhathi ebizwa ngokuthi i-Hydroxyprogesterone (isiNgisi: hydroxyprogesterone, OHP), iyi-progesterone steroid engapheli efana ne-progesterone, futhi iyisandulela se-biosynthesis yamahomoni amaningi e-endogenous steroid, okuhlanganisa i-androgen, i-estrogen, i-glucocorticoid, i-mineralocorticoid kanye ezinye neurosteroids.I-Bioactive 17-Hydroxyprogesterone (17-OHP) iyi-progesterone engapheli kanye nekhemikhali emaphakathi ku-biosynthesis yamanye amahomoni e-steroid.Izifundo ze-in vitro 17 α- OHP iyi-progesterone efana ne-chemobookin receptor agonist, nakuba umphumela wayo ubuthakathaka.Kuphinde kube yikhemikhali emaphakathi ku-biosynthesis yamahomoni e-steroid afana ne-androgens, i-estrogen, amahomoni ocansi, i-glucocorticoids, ne-mineralocorticoids.Ucwaningo lwe-in vivo lwe-17 I-Hydroxyprogesterone iyi-steroid inducer esebenzayo ye-GVBD (ukuqhekeka kwe-vesicle yokuzala).Izici zamakhemikhali crystallization (i-acetone/hexane).Iphoyinti lokuncibilika 221 ℃ (219-220 ℃).[ α] 20/D+97 ° (chlorofor